Misoora Skincare
Retinal 0.2% Barrier Serum for Mature, Sensitive Skin
$35.00
Gentle retinal night serum for mature, sensitive skin. Smoother-looking lines and texture, without the retinol drama.
Retinaldehyde — the form of vitamin A one step from retinoic acid — at 0.2%, a level chosen for tolerance, buffered with a full barrier complex so mature skin can use it night after night.
If retinol ever left you red, flaking or quitting after two weeks, you're not alone. Mature skin is drier and recovers more slowly, and most vitamin A routines are simply too harsh for it.
Retinol has to convert twice before skin can use it. Retinal converts once. That's why 0.2% retinal can do meaningful work at a gentle level. Ceramide NP, centella, beta-glucan and bisabolol keep skin comfortable, while ergothioneine and vitamin E act as antioxidants overnight.
- Smoother-looking fine lines and texture with consistent evening use
- More even, radiant-looking tone
- Buffered with ceramides to minimize flaking and dryness
- Fragrance-free; airless pump keeps retinal stable to the last drop
- About 60 applications per bottle
- PM only. Wear SPF daily; don't layer with other vitamin A or strong exfoliants
Retinal 0.2% Barrier Serum for Mature, Sensitive Skin
Gentle retinal night serum for mature, sensitive skin. Smoother-looking lines and texture, without the retinol drama.
Retinaldehyde — the form of vitamin A one step from retinoic acid — at 0.2%, a level chosen for tolerance, buffered with a full barrier complex so mature skin can use it night after night.
If retinol ever left you red, flaking or quitting after two weeks, you're not alone. Mature skin is drier and recovers more slowly, and most vitamin A routines are simply too harsh for it.
Retinol has to convert twice before skin can use it. Retinal converts once. That's why 0.2% retinal can do meaningful work at a gentle level. Ceramide NP, centella, beta-glucan and bisabolol keep skin comfortable, while ergothioneine and vitamin E act as antioxidants overnight.
- Smoother-looking fine lines and texture with consistent evening use
- More even, radiant-looking tone
- Buffered with ceramides to minimize flaking and dryness
- Fragrance-free; airless pump keeps retinal stable to the last drop
- About 60 applications per bottle
- PM only. Wear SPF daily; don't layer with other vitamin A or strong exfoliants
Estimated delivery: November 09.
Free US shipping on orders $40+
Retinal results, without the irritation
0.2% retinaldehyde with barrier support smooths lines and texture, gentle enough for sensitive, mature skin. At night, apply a pea-sized amount to dry skin, avoiding the eyes. Start with 2–3 nights a week. Wear SPF in the morning.
MISOORA evening routine. Built to work together
Reviews
- CACarol A.Rated 5 out of 5 stars2 weeks agoreally liking this
No crazy dryness or anything like that. I’m gonna keep using it because I really like how my skin looks lately. Simple and works for me!
- SPSusan p.Rated 5 out of 5 stars2 weeks agoDidn’t expect to like retinal this much
I was a little nervous to try retinal but it feels smoother and just looks a little fresher. I like that my face doesn’t feel dry after using it either. I’m gonna keep using it and see how it goes.
- KKatherineVerified ReviewerRated 5 out of 5 stars3 months agoSo Glad I Listened to My Esthetician
This was my first time using a retinal serum, and I'm so glad I took my esthetician's recommendation! I was a little surprised by the bright yellow color at first, but after seeing the results, I completely understood why everyone loves retinal.
The serum feels lightweight, absorbs quickly, and layers beautifully with the rest of my skincare. After just a short time, my skin looked smoother, brighter, and more even. I wake up every morning with healthy-looking, glowing skin.
This has officially become a must-have in my routine. I honestly can't imagine my skincare without it now!
- SSydnieVerified ReviewerRated 5 out of 5 stars4 months agoEffective, but not aggressive
I’ve been using different retinol products for over a year, and honestly, I was starting to feel frustrated. Most of them either felt too harsh or didn’t really do much.
Misoora Retinal 0.2% is the first retinal serum that feels like it actually works with my skin, not against it.
It’s strong enough to feel like it’s actually working, but still comfortable on my skin. No heavy irritation, no “my skin is angry” feeling, just smoother, fresher-looking skin over time.
I also love that it supports the skin barrier, because with retinal, that really matters.
- BLBeatrice L.Verified ReviewerRated 5 out of 5 stars4 months agofinally a retinal for rosacea-prone skin
I'm rosacea prone so retinoids usually = disaster. This one I worked up very slowly and my skin tolerated it beautifully. No new flushing. After 6 weeks my complexion is more unified and those tomato-toned patches on my cheeks have calmed. Cautiously thrilled.
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Retinal 0.2% Barrier Serum FAQ
What is the Retinal 0.2% Barrier Serum?
A gentle night serum with 0.2% encapsulated retinaldehyde (retinal) for mature, sensitive skin. It smooths the look of fine lines and texture and evens tone, buffered with a ceramide barrier complex. Size: 30 ml, about 60 applications; regular price $35.
What is the difference between retinal, retinol and tretinoin?
Skin must convert vitamin A into retinoic acid before it can use it. Retinol needs two conversion steps, retinal needs one, and tretinoin is retinoic acid itself (prescription only). Retinal therefore works more directly than retinol and is usually better tolerated than tretinoin.
Why 0.2% retinal?
0.2% is a level chosen for tolerance on drier, slower-to-recover mature skin. The retinal is encapsulated for gradual release, which helps limit redness and flaking.
What are the key ingredients?
Encapsulated retinaldehyde 0.2%, ceramide NP, centella asiatica, beta-glucan, bisabolol and allantoin for comfort, plus ergothioneine and vitamin E as antioxidants. The full ingredient list is on this page.
How do I start using retinal without irritation?
Use it at night only: apply a pea-sized amount to completely dry skin, avoiding the eyes. Start 2–3 nights a week for the first 2 weeks, then every other night, and nightly from month 2 if skin stays comfortable. Wear SPF 30+ every morning.
Is some dryness or peeling normal?
Mild dryness or light flaking in the first weeks is a normal adjustment. Use a moisturizer afterwards, and if your skin feels uncomfortable, use retinal less often until it settles.
What can I combine it with?
Pair it with the PDRN Exosome EGF Night Renewal Serum (retinal first, then PDRN) and the Ceramide+ Barrier Repair Moisturizer. Use the NAD+ Firming Serum in the morning. Do not layer it with other vitamin A products or strong exfoliating acids on the same night.
Is it suitable for sensitive skin?
Yes. It is formulated for mature, sensitive skin, fragrance-free, and packed in an airless pump that keeps retinal stable to the last drop.
Can I use retinal during pregnancy or breastfeeding?
No. Avoid all retinoids, including retinal, during pregnancy and breastfeeding, and ask your doctor before use.
How long until I see results?
Texture usually looks smoother within 4–8 weeks, and fine lines look softer after 8–12 weeks of consistent use. Individual results vary.
Is it tested and cruelty-free?
Yes. The serum is MoCRA registered and FDA listed, cruelty-free, and third-party tested for microbiology, heavy metals and 1,4-dioxane. Certificates of analysis are available on request.
Where can I buy it, and how can I save?
On misoora.com and on Amazon. It is included in the Evening Routine PM Set and the Skin Recharge Set, and Subscribe & Save saves up to 20%.
How much is shipping, and how fast will my order arrive?
Standard shipping is free within the US on orders of $40 or more and on every Subscribe & Save order. Standard delivery takes about 5–7 business days; faster options and international rates are shown at checkout.
What is the return policy?
You can request a return within 30 days of delivery. Email care@misoora.com with your order number, and see our Return Policy for the conditions.
From the Journal
Read before you start
Guides about this product, the routine it belongs to and mature skin in general.
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Collagen powder may help hydration a little, but newer reviews find no reliable effect on wrinkles. Here is what the research says for skin after menopause, and what has a stronger case.
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Ozempic Face After Menopause: Why GLP-1 Weight Loss Shows on Your Face, and What Helps
Why GLP-1 weight loss can make your face look hollow or looser after menopause, what the research shows, and the retinal, moisturizer and SPF routine that helps skin look firmer.
Read the guide →
Estrogen Face Cream After Menopause: Does It Work, Is It Safe, and What Else Helps?
Estrogen face creams are trending, but the evidence is thin. What the studies show, the risks, and the retinal routine to use instead.
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Our mission
At MISOORA, we believe growing older is a privilege, not a flaw to mask or apologize for. True beauty isn't about chasing unachievable, frozen-in-time standards. It lies in skin resilience and health, and in honoring where you are right now.
Longevity
We wanted every MISOORA product to support you through perimenopause, menopause, and beyond. To guide you on this journey, we made longevity skincare that works as a system, not a collection of disconnected products, formulated to meet the needs of your changing skin.
Transparency
We believe you deserve total honesty. MISOORA discloses exact active concentrations and 100% clean ingredients, fully verified by MoCRA registration, FDA listing, and third-party testing. So you can feel completely confident in gentle, barrier-friendly formulas built to honor, protect, and support your skin as you age.
Safety
Always the best and safest ingredients out there. Because MISOORA focuses on nourishing your skin rather than harsh chemical exfoliation, every formula is delightfully gentle, ethanol-free, and suitable for all skin types, including sensitive. Created for the unique, evolving needs of skin in your 50s, 60s, 70s, and beyond.
Science
All our products are formulated with the best ingredient selection and carefully tested specifically for mature skin needs:
NAD+ → To recharge aging skin cells.
PDRN → To refine texture.
Exosomes → To boost firmness.
EGF → To stimulate natural collagen.
Retinaldehyde → To soften wrinkles.
Ceramides → To rebuild the barrier.
Centella → To reduce irritation.
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- ✓Smooths the look of lines and uneven texture
- ✓0.2% retinaldehyde, buffered with ceramides and centella
- ✓Made for skin that got red and flaky on retinol
Best forLinesTextureEvening
- Free US shipping on orders $40+
- Easy 30-day returns
- Fragrance-free formula
- Third-party safety tested
Better as a set
Evening Routine PM Set
Includes this plus Centella Cleanser, PDRN serum and Ceramide+ Moisturizer.
$78$104Save $26