Multi-peptide firming serum for mature skin. Visibly firmer, smoother-looking skin with more radiance.

A NAD+ and peptide serum that recharges tired-looking skin — for skin that looks firmer, lifted and more rested in weeks, not months.

After menopause, skin loses more than estrogen. It loses fuel. NAD+ — the molecule your cells use to renew themselves — declines with age. Less energy, slower renewal, skin that looks thinner and flatter than it did five years ago. That's the tiredness no ordinary cream reaches.

Mature skin is also slower to recover, so nothing here strips it. 2,500 ppm of NAD+, disclosed, plus NMN and ATP, in a barrier complex of ceramide NP, cholesterol and linoleic acid — the lipids mature skin makes less of. Firmer, denser-looking skin. No peeling, no stinging, no downtime.

• 93% saw firmer-looking skin in 4 weeks
• Softer-looking fine lines, smoother-looking texture
• Zero irritation reported — no purging, no peeling, no sun sensitivity
• Fragrance-free and ethanol-free — gentle on mature, sensitive skin
• Face, neck and jawline — where thinning shows first
• Layers with everything you already use, including retinal

Save $35 with the MISOORA Skin Recharge Set

Night renewal serum for thin, tired-looking mature skin.
Smoother, bouncier, more even-looking skin, night after night.

Three biotech actives from the world of aesthetic treatments — PDRN, exosomes and EGF — in one gentle evening step, so skin looks denser, smoother and more rested with consistent use.

With age, skin renews more slowly. After menopause it often looks thinner, more fragile and slower to bounce back. Night is when skin does most of its recovery, and this serum is built for that window.

2,000 ppm PDRN, 50 ppm exosomes and 20 ppm EGF — disclosed, not hidden in a blend. Palmitoyl tripeptide-1, 1.5% panthenol and asiaticoside sit in a base of ceramide NP, cholesterol and linoleic acid, so a renewal serum still feels calm on sensitive skin.

• Smoother, denser-looking skin with nightly use
• Softer-looking fine lines, more even-looking tone
• Fragrance-free, alcohol-free, no essential oils
• Pairs with Retinal 0.2%: retinal first, then PDRN
• Face and neck, 1–2 drops every evening
• Contains salmon-derived PDRN (not vegan)

Complete your night routine with the Evening PM Set

Gentle retinal night serum for mature, sensitive skin. Smoother-looking lines and texture, without the retinol drama.

Retinaldehyde — the form of vitamin A one step from retinoic acid — at 0.2%, a level chosen for tolerance, buffered with a full barrier complex so mature skin can use it night after night.

If retinol ever left you red, flaking or quitting after two weeks, you're not alone. Mature skin is drier and recovers more slowly, and most vitamin A routines are simply too harsh for it.

Retinol has to convert twice before skin can use it. Retinal converts once. That's why 0.2% retinal can do meaningful work at a gentle level. Ceramide NP, centella, beta-glucan and bisabolol keep skin comfortable, while ergothioneine and vitamin E act as antioxidants overnight.

• Smoother-looking fine lines and texture with consistent evening use
• More even, radiant-looking tone
• Buffered with ceramides to minimize flaking and dryness
• Fragrance-free; airless pump keeps retinal stable to the last drop
• About 60 applications per bottle
• PM only. Wear SPF daily; don't layer with other vitamin A or strong exfoliants

Pair it with PDRN in the Evening PM Set

Gentle, non-stripping cleanser for mature, sensitive skin.
Clean skin without tightness — the first step of every routine.

A sulfate-free, pH-balanced amino acid cleanser with centella and ceramides that removes the day without taking your barrier with it.

Most cleansers are made for oily, younger skin. On mature skin they leave that squeaky, tight feeling — a sign the barrier has been stripped, and the reason serums sting afterward.

Amino acid cleansing agents gently lift away makeup, SPF and oil, while centella calms and ceramides keep skin comfortable. Clean, soft skin, ready for your actives.

• No tight, squeaky feeling after rinsing
• Sulfate-free and pH-balanced
• Fragrance-free
• Morning and evening
• Pat skin damp, not dry, before your serum

Start your routine with the Skin Recharge Set

Barrier repair moisturizer for dry, mature skin.
Softer, calmer, more comfortable skin, morning and night.

The final step of every MISOORA routine: a ceramide-rich moisturizer that seals in your serums and helps dry, mature skin hold on to moisture.

After 50, skin makes fewer of its own barrier lipids. The signs are familiar: tightness after cleansing, flaky patches, makeup that clings, and skin that suddenly reacts to products it used to tolerate.

Ceramide+ is built around the lipids a healthy barrier relies on, so skin feels cushioned, not coated. It also makes stronger actives — NAD+, PDRN, retinal — easier to live with every day.

• Relieves tightness and dryness from the first use
• Seals in serums and keeps skin comfortable during retinal use
• Fragrance-free and ethanol-free
• Face and neck, morning and evening

Part of the Morning AM Set and the Skin Recharge Set