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Evening Skincare Routine Set PM — Retinal, PDRN + Exosome + EGF Anti-Aging Night Routine

5.0
Rated 5.0 out of 5 stars
2 Reviews

Your skin repairs overnight. Make it count.

Four clinic-grade formulas. One complete PM system. MISOORA Skin Recharge Skincare builds the evening routine your skin needs — from a gentle amino acid cleanse to the deepest retinal + PDRN repair cycle available in a DTC skincare set.

EMPTY DOM REMOVE PROTECTOR
EMPTY DOM REMOVE PROTECTOR
EMPTY DOM REMOVE PROTECTOR
EMPTY DOM REMOVE PROTECTOR
EMPTY DOM REMOVE PROTECTOR
EMPTY DOM REMOVE PROTECTOR

What the Full PM System Delivers

Accelerated Cell Turnover Overnight

Retinal 0.2% drives keratinocyte renewal and stimulates collagen synthesis while you sleep — the window when your skin's natural repair cycle peaks. By morning, skin texture is visibly smoother. With consistent use, fine lines fade and pore appearance reduces. The anti-inflammatory buffer system (Bisabolol, Centella Asiatica, Beta-Glucan) ensures this happens without the redness and flaking typical of retinoid introductions.

Deep Regeneration with PDRN + Exosome Technology

PDRN (polynucleotide) at 2,000ppm activates A2A receptors to trigger the body's own DNA repair pathways — a mechanism used in clinical aesthetic treatments. Combined with 50ppm exosome signaling and EGF at 20ppm, this serum creates a regenerative environment at the cellular level. Applied post-retinal, the permeability window ensures the complex reaches where it can perform.

Barrier Reinforcement at Every Step

Retinoids can compromise the skin barrier — which is why this routine was designed to rebuild it at every step. The cleanser deposits Ceramide NP, the retinal serum includes its own ceramide-cholesterol complex, and the final moisturizer delivers the highest ceramide concentration in the range. Your barrier is never left vulnerable overnight.

Visible Firming and Even Tone with Sustained Use

Matrixyl 3000 (Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7) in the barrier moisturizer supports collagen and elastin synthesis alongside retinal's structural renewal. Paired with PDRN's regenerative signal, the combined effect is measurable: firmer skin by Month 2, more even tone by Month 3. This is not a one-serum promise — it is a system result.

Your MISOORA routine. Built to work together

Step 1 — MISOORA Cleanser

Start with a gentle, pH-balanced cleanser. Pat skin until damp — not dripping. Damp skin absorbs actives faster and deeper. 

Step 2 — MISOORA Retinal Serum

Evening is when retinal works best — skin repair cycles peak overnight. Apply before PDRN on dry skin.

Step 3 — MISOORA PDRN+EXOSOME+EGF Serum

PDRN (Polydeoxyribonucleotide) is a cellular repair signal that works synergistically with retinal. Apply immediately after retinal, press gently in.

Step 3 — MISOORA Moisturizer

Seal the serum in with your moisturizer. Follow immediately with SPF 30 or higher. The moisturizer locks the NAD+ actives in place and extends their working time through the day. 

Reviews

5.0
Rated 5.0 out of 5 stars
Based on 2 reviews
Total 5 star reviews: 2 Total 4 star reviews: 0 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
100%would recommend this product
2 reviews
  • S
    Siobhan
    Verified Reviewer
    I recommend this product
    Rated 5 out of 5 stars
    A must-try!

    Okayyy, can we talk about how GOOD this skincare set is?!

    I've been using the whole evening anti-aging routine, and girl... my skin is looking SO good. It's smoother, brighter, more even, and has that healthy glow that makes you want to leave the house without makeup.

    And listen, the retinal and PDRN serum? Absolute MVPs. The retinal has my skin looking fresh and refined, and the PDRN makes it feel so plump, juicy, and hydrated. I wake up every morning like, Wait... is this really my skin?

    No joke, this is one of the best skincare investments I've ever made. Every product works beautifully together, and the results speak for themselves. I'm obsessed.

  • AF
    Adrian F.
    I recommend this product
    Rated 5 out of 5 stars
    Retinal + PDRN = no irritation

    I always wanted to use a retinal but feared the flaking. Pairing it with the PDRN in this set was the trick, the PDRN keeps my barrier strong so the retinal does its anti-aging thing without any of the dryness or redness. Smart bundle. My fine lines are softening.

Frequently Asked Questions

The Cleanser, PDRN+Exosome+EGF Serum, and Ceramide Barrier Moisturizer can be used nightly from day one. The Retinal Awakening Serum requires a gradual introduction: every other night for weeks 1–2, then nightly from week 3 onward. This schedule minimizes initial sensitivity while building skin tolerance.

Retinal (retinaldehyde) is one conversion step closer to retinoic acid than retinol. This means it works faster and delivers results at lower concentrations. MISOORA uses Retinal at 0.2% — effective without the prolonged adjustment period typical of retinol. The formula also includes a dedicated anti-inflammatory system (Bisabolol 0.5%, Beta-Glucan 0.5%, Centella Asiatica 0.8%) to reduce redness and peeling during the introduction phase.

 Retinal is most effective — and best tolerated — on completely dry skin. Applying to damp skin increases absorption speed and can cause irritation, especially during the first weeks of use. Wait 3–5 minutes after cleansing before applying the Retinal Awakening Serum.

Retinal creates a temporary increase in skin permeability as it accelerates cell turnover. Applying PDRN+Exosome+EGF immediately after retinal allows the regenerative actives to penetrate more deeply into the dermis. This sequencing is intentional and maximizes the efficacy of both formulas.

Days 1–7: Recovery begins — skin barrier activates, PDRN starts the repair cycle, less redness. Days 8–21: Regeneration becomes visible — skin texture smooths, exosome cell signaling intensifies. Month 2: Structural renewal — retinal-driven cell turnover compounds alongside PDRN collagen support. Month 3+: Sustained firming, clarity, and even tone maintained overnight.

The PM set includes Retinal, which requires a careful introduction for sensitive skin. The formula is designed to minimize this with a comprehensive anti-inflammatory system. Start every other night. If redness or peeling occurs, extend the every-other-night phase by an additional week before moving to nightly use. The PDRN serum and Moisturizer are both suitable for sensitive skin from day one.

No. The Evening Routine Set PM contains Retinal, a vitamin A derivative. Retinoids are not recommended during pregnancy or breastfeeding. Consult your healthcare provider before use. The AM Routine Set (Cleanser + NAD+ + Moisturizer) does not contain retinoids and may be an alternative — confirm with your doctor.

The PM and AM sets form a complete 24-hour Skin Recharge system. The AM set activates cellular energy and builds daytime barrier defense. The PM set drives overnight regeneration, cell turnover, and deep repair via Retinal and PDRN. The Ceramide Barrier Moisturizer is shared across both routines, ensuring barrier reinforcement morning and night.